In order to be able to continually offer the finest solutions in Oral Healthcare, taking on the challenge of studying and fully comprehending bacterial behaviour is top priority for the R&D&i team at DENTAID.
Along these lines, the company developed an in vitro study model known as the Artificial Mouth, whose 3 main purposes are:
- To have a system that allows us to grow a biofilm in vitro, by reproducing the complex conditions of the oral environment.
- To study and understand the behaviour of the diverse bacterial species that form oral biofilms.
- To assess the efficacy of antiseptic rinses, such as Perio·Aid, in controlling biofilm.
To validate the Artificial Mouth model, the microbiology team at the DENTAID Research Center submitted their study entitled Characterization and application of a flow system for in vitro multispecies oral biofilm formation, which was published in the prestigious Journal of Periodontal Research in May 2013.
The findings were conclusive and prove that the Artificial Mouth is a highly reproducible and useful model for evaluating the interactions between the bacteria that form supra- and subgingival biofilms, as well as for assessing the antimicrobial activity of antiseptic molecules for oral use. The study also determines that Perio·Aid’s antibacterial activity is greater, even in the deepest layers of the oral biofilm, compared to other rinses containing Chlorhexidine, a fact that is demonstrated with the Artificial Mouth model.