Peri-implant mucositis has a low potential for inflammatory response, and thus, when oral biofilm accumulation exists, the inflammation spreads deeper, possibly causing implant loss. Peri-implantitis has an
Because peri-implant tissues have a lower capacity to react to the accumulation of oral biofilm compared to periodontal tissues, peri-implant disease is highly prevalent among implant patients.
Periodontitis is the most advanced form of gum disease and can potentially have an impact on a systemic level, with a prevalence of 35.4% in adults between
Among the different forms of gum disease, gingivitis is the most common to occur in humans, with a prevalence of 59.8% in adults between the ages of
The data reflects the importance of biofilms as a source for local infections that can trigger complications on a systemic level.
Many non-pathogenic organisms exist that produce
initiative 
